Focal adhesion kinase (FAK) is a cytoplasmic protein tyrosine kinase that plays a key role in regulating cell adhesion, migration, and survival. It is involved in the formation and signaling of focal adhesions, which are dynamic structures that link the extracellular matrix to the actin cytoskeleton. FAK is also implicated in various cellular processes such as cell proliferation, differentiation, and angiogenesis. Research on FAK has shown its involvement in cancer progression, as its overexpression or aberrant activation has been linked to increased tumor cell survival, invasion, and metastasis. Therefore, targeting FAK has emerged as a potential therapeutic strategy for cancer treatment. Additionally, FAK has been studied in the context of other diseases such as cardiovascular disorders, fibrosis, and neurological conditions. Understanding the molecular mechanisms underlying FAK signaling can provide insights into disease pathogenesis and help in the development of targeted therapies.